09.15 Registration and Coffee

10.00 Welcome and Introduction

10.05 PLENARY LECTURE: Pattern recognition and grid computing in drug discovery

Professor Graham Richards (University of Oxford)

10.50 Bioinformatics and structural biology in drug design

Dr Neera Borkakoti (Medivir UK Ltd)

11.20 Coffee

11.50 Selecting druggable targets

Dr James E Mills (Pfizer)

12.20 Structure-based fragment screening and its application to drug design

Dr Chris Murray (Astex Technology)

12.50 Lunch

13.50 Elucidation and exploitation of molecular mechanisms in drug discovery

Dr Walter Ward (AstraZeneca)

14.20 Integrating ADME properties and applying them in drug design

Dr Mike Tarbit (ArQule UK Ltd)

14.50 Tea

15.15 Application of Quasi2, an extended pharmacophore generation and vHTS program, to a range of targets including kinases and GPCRs

Dr David Manallack (De Novo Pharmaceuticals)

15.45 Ligand recognition at GPCR receptors – Variations on a theme

Dr Roger Crossley (BioFocus plc)

16.15 Ion channels – where next?

Dr Brian Cox (Novartis Pharmaceuticals)

16.45 Close